OR5AP2

Across TCGA pan-cancer cohorts, OR5AP2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated OR5AP2 data layer compared with 6 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OR5AP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR5AP2 expression acts as an unfavorable survival marker.

ACC, KIRC, and PAAD are the cancer types where OR5AP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.010	0.667	<.001	135	view →
KIRC	DFS	Tertile	III,IV	0.277	0.510	<.001	135	view →
PAAD	OS	Tertile	All	0.189	0.624	<.001	99	view →
LIHC	OS	Tertile	II,III,IV	0.212	0.792	<.001	90	view →
COAD	OS	Tertile	All	0.163	0.870	<.001	54	view →
BLCA	OS	Tertile	IV	0.063	0.576	<.001	45	view →
ESCA	OS	Quartile	II,III,IV	0.330	1.000	.001	36	view →
OV	OS	Tertile	III,IV	0.611	0.841	.006	24	view →
KICH	DFS	Tertile	All	0.121	0.867	.023	15	view →
GBM	OS	Tertile	All	0.075	0.416	.011	9	view →
THYM	DFS	Tertile	All	0.134	0.871	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

OR5AP2–ACC (DFS)

Open the ACC breakdown →