OR5AP2

Across TCGA cell cohorts, OR5AP2 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR5AP2-associated genes across cancer lineages are C1orf87, SLCO1C1, and PRB3. Each is linked with OR5AP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AP2-to-partner and partner-to-OR5AP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1orf87 grouped by OR5AP2-low versus OR5AP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AP2→partner) and Y-score (partner→OR5AP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C1orf87 →	+0.025	+5.201	<.001	.006	3	2
BLOOD_Myeloma	SLCO1C1 →	+0.039	+3.285	<.001	.009	3	1
BLOOD_Myeloma	PRB3 →	+0.261	+3.514	.003	.008	3	1
SKIN	UCP1 →	+0.134	+3.684	.003	.009	3	1
SKIN	TMEM235 →	+0.009	+4.217	<.001	.001	3	1
SKIN	METTL24 →	+0.391	+3.920	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

C1orf87 by OR5AP2 expression — BLOOD_Leukemia

Explore this box plot interactively →