OR5AK2

Across TCGA cell cohorts, OR5AK2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OR5AK2-associated genes across cancer lineages are OR1J2, OR10H2, and CCR8. Each is linked with OR5AK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AK2-to-partner and partner-to-OR5AK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1J2 grouped by OR5AK2-low versus OR5AK2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AK2→partner) and Y-score (partner→OR5AK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR1J2 →	+0.044	+4.635	<.001	.003	3	2
SOFT_TISSUE	OR10H2 →	+0.136	+4.369	<.001	.008	3	1
SOFT_TISSUE	CCR8 →	+0.016	+4.369	<.001	.008	3	1
SOFT_TISSUE	RTL4 →	+0.016	+4.369	.001	.008	3	1
SOFT_TISSUE	SERPINB11 →	+0.847	+4.222	<.001	.007	3	1
SOFT_TISSUE	GSG1L2 →	+0.299	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR1J2 by OR5AK2 expression — SOFT_TISSUE

Explore this box plot interactively →