OR5AC2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR5AC2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR5AC2-associated genes across cancer lineages are JNK_pT183_Y185, MIG-6, and Notch1. Each is linked with OR5AC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5AC2-to-partner and partner-to-OR5AC2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5AC2→partner) and Y-score (partner→OR5AC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCJNK_pT183_Y185 →-0.120-2.312.022.03532
UCECMIG-6 →+0.156+2.183.002.03532
UCECNotch1 →+0.228+3.009.002.01932
UCECPCNA →+0.366+3.321.001.01032
UCECAR →-0.657-3.321<.001.01032
LUSCHER3_pY1289 →-0.085-2.972.043.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

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