OR5AC2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, OR5AC2 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated OR5AC2 data layer compared with 5 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher OR5AC2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OR5AC2 expression acts as an unfavorable survival marker.

BLCA, OV, and LIHC are the cancer types where OR5AC2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSTertileAll0.2300.621<.001144view →
OVOSTertileIII,IV0.4730.839.00778view →
LIHCDFSTertileAll0.0800.553.00427view →
UCECOSTertileIII,IV0.2660.606.03224view →
LGGDFSTertileAll0.4440.765.0099view →
STADDFSTertileIV0.0830.379.0019view →
LUADOSTertileII,III,IV0.2480.590.0339view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration