OR5A2

Across TCGA pan-cancer cohorts, OR5A2 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated OR5A2 data layer compared with 7 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR5A2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR5A2 expression acts as an unfavorable survival marker.

COAD, KIRC, and SARC are the cancer types where OR5A2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.056	0.871	<.001	48	view →
KIRC	OS	Median	All	0.138	0.655	.019	12	view →
SARC	DFS	Median	All	0.096	0.632	.003	12	view →
CESC	OS	Median	All	0.151	0.798	<.001	12	view →
LUSC	OS	Median	All	0.011	0.819	<.001	6	view →
SKCM	DFS	Median	III,IV	0.087	0.647	.013	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

OR5A2–COAD (OS)

Open the COAD breakdown →