OR5A2

Across TCGA patient cohorts, OR5A2 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR5A2-associated genes across cancer lineages are CMP, Eosinophils, and Epithelial cells. Each is linked with OR5A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR5A2-to-partner and partner-to-OR5A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by OR5A2-low versus OR5A2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR5A2→partner) and Y-score (partner→OR5A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CMP →	+0.020	+1.993	<.001	.022	3	2
LUSC	Eosinophils →	+0.022	+1.851	.011	.032	3	1
UCEC	Epithelial cells →	-0.094	-3.321	.012	.010	3	1
LUSC	DC →	-0.024	-3.298	.038	.010	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CMP by OR5A2 expression — LUSC

Explore this box plot interactively →