OR56B4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR56B4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR56B4-associated genes across cancer lineages are ST6GAL2 and ACER1. Each is linked with OR56B4 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR56B4-to-partner and partner-to-OR56B4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ST6GAL2 grouped by OR56B4-low versus OR56B4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56B4→partner) and Y-score (partner→OR56B4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEST6GAL2 →+0.846+3.617<.001.00431
LARGE_INTESTINEACER1 →+0.071+3.145.008.00431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ST6GAL2 by OR56B4 expression — LARGE_INTESTINE

Box plot of ST6GAL2 in OR56B4-low vs OR56B4-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration