OR56A4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR56A4 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR56A4-associated genes across cancer lineages are Chk2, MSH6, and Cyclin-B1. Each is linked with OR56A4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR56A4-to-partner and partner-to-OR56A4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56A4→partner) and Y-score (partner→OR56A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCChk2 →+0.301+3.000.025.03533
LUSCMSH6 →+0.425+3.179.034.01032
LUSCCyclin-B1 →+0.771+3.179<.001.01032
UCECKu80 →+0.279+2.128.006.01032
UCECRab11 →-0.135-2.999.033.03532
LUSCFibronectin →-0.631-3.000.007.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration