OR56A1

Across TCGA patient cohorts, OR56A1 mutation is significantly associated with the RNA expression of many other genes, with 672 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR56A1-associated genes across cancer lineages are CICP28, MIR4266, and RBBP4. Each is linked with OR56A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR56A1-to-partner and partner-to-OR56A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CICP28 grouped by OR56A1-low versus OR56A1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR56A1→partner) and Y-score (partner→OR56A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CICP28 →	+0.015	+2.856	<.001	.002	3	3
BRCA	MIR4266 →	+0.354	+7.731	<.001	.009	3	2
LUSC	RBBP4 →	+0.522	+3.596	.003	.001	3	2
LUSC	CPB2-AS1 →	+0.300	+3.605	<.001	.001	3	2
LUSC	MOCS1P1 →	+0.119	+2.397	.006	.003	3	2
LUSC	LINC02136 →	+0.186	+2.518	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 672 associations by consensus.

CICP28 by OR56A1 expression — LUAD

Explore this box plot interactively →