OR52W1

Across TCGA patient cohorts, OR52W1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52W1-associated genes across cancer lineages are JNK_pT183_Y185, p62 Lck ligand, and STAT5a. Each is linked with OR52W1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52W1-to-partner and partner-to-OR52W1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by OR52W1-low versus OR52W1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52W1→partner) and Y-score (partner→OR52W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.203	-3.156	.028	.020	3	1
UCEC	p62 Lck ligand →	+0.504	+2.817	.004	.036	3	1
UCEC	STAT5a →	+0.444	+3.000	.043	.036	3	1
UCEC	c-Met_pY1235 →	+0.084	+2.817	.038	.036	3	1
UCEC	C-Raf →	+0.207	+3.000	.008	.036	3	1
UCEC	p70-S6K_pT389 →	-0.285	-3.169	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

JNK_pT183_Y185 by OR52W1 expression — UCEC

Explore this box plot interactively →