OR52W1

Across TCGA cell cohorts, OR52W1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52W1-associated genes across cancer lineages are C6orf118, TCF15, and DEFA4. Each is linked with OR52W1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52W1-to-partner and partner-to-OR52W1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by OR52W1-low versus OR52W1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52W1→partner) and Y-score (partner→OR52W1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.148	+4.378	<.001	<.001	3	1
LARGE_INTESTINE	TCF15 →	+0.350	+2.878	.007	.009	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1
LARGE_INTESTINE	GPR171 →	+0.014	+3.103	.001	.004	3	1
LARGE_INTESTINE	NPY2R →	+0.003	+3.217	<.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.109	+3.103	.005	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

C6orf118 by OR52W1 expression — LARGE_INTESTINE

Explore this box plot interactively →