OR52N2

Across TCGA patient cohorts, OR52N2 mutation is significantly associated with the RNA expression of many other genes, with 515 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N2-associated genes across cancer lineages are MTND4LP31, CTBP2P9, and GZMH. Each is linked with OR52N2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR52N2-to-partner and partner-to-OR52N2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND4LP31 grouped by OR52N2-low versus OR52N2-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N2→partner) and Y-score (partner→OR52N2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MTND4LP31 →	+0.066	+4.099	<.001	.008	3	4
SKCM	CTBP2P9 →	+0.021	+2.758	<.001	.003	3	2
UCEC	GZMH →	+1.463	+3.354	<.001	.005	3	2
UCEC	IFNG →	+1.025	+3.384	<.001	.004	3	2
UCEC	RN7SKP214 →	+0.309	+2.142	<.001	.005	3	2
UCEC	RNA5SP293 →	+0.083	+4.360	.004	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 515 associations by consensus.

MTND4LP31 by OR52N2 expression — LUSC

Explore this box plot interactively →