OR52M1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR52M1 mutation is significantly associated with the RNA expression of many other genes, with 190 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52M1-associated genes across cancer lineages are DMRTC1, OOSP2, and KRTAP13-2. Each is linked with OR52M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52M1-to-partner and partner-to-OR52M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52M1→partner) and Y-score (partner→OR52M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINDMRTC1 →+0.035+4.022<.001.00632
CNSOOSP2 →+0.128+5.321<.001.00531
CNSKRTAP13-2 →+0.134+4.981<.001.00831
CNSMBD3L4 →+0.019+5.321<.001.00531
CNSOOSP4B →+0.229+5.754<.001.00231
BLOOD_LeukemiaGFRA4 →+0.301+4.409.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 190 associations by consensus.

Exploration