Across TCGA cell cohorts, OR52L1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52L1-associated genes across cancer lineages are H1-8, DUSP21, and OR2F2. Each is linked with OR52L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52L1-to-partner and partner-to-OR52L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52L1→partner) and Y-score (partner→OR52L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	H1-8 →	+0.044	+4.887	<.001	.009	3	1
LUNG_SCLC	DUSP21 →	+0.035	+5.029	<.001	.006	3	1
LUNG_SCLC	OR2F2 →	+0.096	+5.643	<.001	.002	3	1
LARGE_INTESTINE	USP29 →	+0.014	+4.415	<.001	.007	3	1
LARGE_INTESTINE	LCE1F →	+0.122	+4.415	<.001	.007	3	1
SKIN	MTNR1B →	+0.029	+4.684	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

OR52L1 survival (RNA) · tumor vs normal (RNA) · all OR52L1 data types