OR52K2

Across TCGA cell cohorts, OR52K2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR52K2-associated genes across cancer lineages are PIP, ITGAD, and OR4D6. Each is linked with OR52K2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52K2-to-partner and partner-to-OR52K2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIP grouped by OR52K2-low versus OR52K2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52K2→partner) and Y-score (partner→OR52K2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PIP →	+0.040	+4.807	<.001	.006	3	1
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4D6 →	+0.557	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	SPINK14 →	+0.267	+4.662	<.001	.005	3	1
BLOOD_Leukemia	DPRX →	+0.109	+5.060	<.001	.001	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PIP by OR52K2 expression — BLOOD_Myeloma

Explore this box plot interactively →