Across TCGA pan-cancer cohorts, OR52K1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated OR52K1 data layer compared with 11 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OR52K1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated OR52K1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

COAD, LUSC, and UCEC are the cancer types where OR52K1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.001	0.871	<.001	18	view →
LUSC	DFS	Median	II,III,IV	0.205	0.594	.031	3	view →
UCEC	DFS	Median	All	1.000	0.629	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: OR52K1 tumor-vs-normal RNA expression · all OR52K1 data types