Across TCGA pan-cancer cohorts, OR52K1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR52K1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR52K1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR52K1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC and KIRC are the cancer types where OR52K1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR52K1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.026	<.001	4	view →
KIRC	All	III,IV	+0.011	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: OR52K1 RNA expression & survival · all OR52K1 data types