Across TCGA patient cohorts, OR52K1 mutation is significantly associated with the RNA expression of many other genes, with 1,034 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52K1-associated genes across cancer lineages are PGAM5, MIR181A1, and LYAR. Each is linked with OR52K1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52K1-to-partner and partner-to-OR52K1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52K1→partner) and Y-score (partner→OR52K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PGAM5 →	+0.558	+2.807	.002	.003	3	3
LUAD	MIR181A1 →	+0.484	+3.343	<.001	.006	3	3
UCEC	LYAR →	+0.585	+2.716	.006	.003	3	3
SKCM	KIF26A →	-0.578	-2.125	.005	.003	3	3
UCEC	FGD5 →	-0.716	-2.807	.003	.003	3	2
UCEC	REEP4 →	+0.529	+2.818	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,034 associations by consensus.

Exploration

OR52K1 survival (RNA) · tumor vs normal (RNA) · all OR52K1 data types