Across TCGA cell cohorts, OR52K1 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR52K1-associated genes across cancer lineages are C6orf118, MRGPRE, and DEFA4. Each is linked with OR52K1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52K1-to-partner and partner-to-OR52K1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52K1→partner) and Y-score (partner→OR52K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.115	+3.793	.002	.007	3	2
BLOOD_Lymphoma	MRGPRE →	+0.019	+5.209	<.001	.005	3	2
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
SKIN	CST9L →	+0.039	+4.415	<.001	.007	3	1
SKIN	SLURP1 →	+0.484	+4.273	<.001	.006	3	1
SKIN	C16orf90 →	+0.031	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

OR52K1 survival (RNA) · tumor vs normal (RNA) · all OR52K1 data types