OR52J3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR52J3 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR52J3-associated genes across cancer lineages are N-Ras, SF2, and EGFR_pY1173. Each is linked with OR52J3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52J3-to-partner and partner-to-OR52J3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52J3→partner) and Y-score (partner→OR52J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMN-Ras →+0.116+2.321.017.00132
UCECSF2 →+0.156+3.013.013.01931
SKCMEGFR_pY1173 →-0.073-1.874.029.04731
SKCMA-Raf_pS299 →+0.104+1.820.043.01431
SKCMp21 →-0.406-1.908.008.00431
SKCMp38-MAPK →+0.160+3.016.009.01831
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration