Across TCGA patient cohorts, OR52I2 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52I2-associated genes across cancer lineages are PKC-b-II_pS660, c-Met_pY1235, and FoxM1. Each is linked with OR52I2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52I2-to-partner and partner-to-OR52I2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52I2→partner) and Y-score (partner→OR52I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-b-II_pS660 →	-0.287	-2.459	.032	.020	3	2
UCEC	c-Met_pY1235 →	+0.086	+2.459	.016	.020	3	2
UCEC	FoxM1 →	+0.257	+2.459	.039	.020	3	1
UCEC	ACVRL1 →	-0.159	-3.302	.015	.010	3	1
UCEC	mTOR_pS2448 →	-0.202	-2.459	.004	.020	3	1
UCEC	Notch1 →	+0.305	+3.584	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

OR52I2 survival (RNA) · tumor vs normal (RNA) · all OR52I2 data types