Across TCGA pan-cancer cohorts, OR52I2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR52I2’s most consistent transcriptional readouts.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where OR52I2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR52I2 is over-expressed in tumor.
PRAD and STAD are the cancer types where OR52I2 tumor–normal differential expression is most reproducible.