OR52I2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR52I2 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52I2-associated genes across cancer lineages are ANKRD66, TMEM132B, and OR6F1. Each is linked with OR52I2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52I2-to-partner and partner-to-OR52I2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52I2→partner) and Y-score (partner→OR52I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTANKRD66 →+0.030+5.781<.001.00131
LARGE_INTESTINETMEM132B →+0.412+3.243.007.00631
LARGE_INTESTINEOR6F1 →+0.040+2.977.001.00631
LARGE_INTESTINEELAC1 →+0.643+3.215.009.00921
LARGE_INTESTINEAPOL4 →+0.627+3.369<.001.00511
LARGE_INTESTINESCML4 →+0.626+3.215.009.00911
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration