OR52I1

Across TCGA patient cohorts, OR52I1 mutation is significantly associated with the RNA expression of many other genes, with 136 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52I1-associated genes across cancer lineages are RPL32P36, RNA5SP432, and RNA5SP146. Each is linked with OR52I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52I1-to-partner and partner-to-OR52I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P36 grouped by OR52I1-low versus OR52I1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52I1→partner) and Y-score (partner→OR52I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL32P36 →	+0.140	+2.448	.009	.008	3	2
UCEC	RNA5SP432 →	+0.798	+2.670	<.001	.009	3	2
UCEC	RNA5SP146 →	+0.503	+2.940	<.001	.005	3	2
LUAD	RPS28P1 →	+0.276	+6.197	<.001	.001	3	2
LUSC	RPL18AP17 →	+0.190	+6.578	<.001	.001	3	2
BLCA	IGKV2D-19 →	+0.198	+4.314	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 136 associations by consensus.

RPL32P36 by OR52I1 expression — UCEC

Explore this box plot interactively →