OR52H1

Across TCGA patient cohorts, OR52H1 mutation is significantly associated with the RNA expression of many other genes, with 1,695 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52H1-associated genes across cancer lineages are TOMM22P5, ATP5MC1P5, and RPS17P11. Each is linked with OR52H1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52H1-to-partner and partner-to-OR52H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOMM22P5 grouped by OR52H1-low versus OR52H1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52H1→partner) and Y-score (partner→OR52H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TOMM22P5 →	+0.675	+3.797	<.001	.003	3	2
COAD	ATP5MC1P5 →	+1.313	+3.790	<.001	.003	3	2
COAD	RPS17P11 →	+0.183	+3.374	.001	.008	3	2
COAD	ATP5MGP7 →	+0.323	+4.020	<.001	.002	3	2
SKCM	SUMO2P1 →	+0.329	+1.954	.009	.008	3	2
SKCM	SAP18P1 →	+0.026	+2.936	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,695 associations by consensus.

TOMM22P5 by OR52H1 expression — COAD

Explore this box plot interactively →