OR52H1

Across TCGA pan-cancer cohorts, OR52H1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of OR52H1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where OR52H1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR52H1 is over-expressed in tumor, although a few such as LUSC and ESCA show the opposite, repressed pattern.

LUSC, KIRC, and ESCA are the cancer types where OR52H1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR52H1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.033	.001	5	view →
KIRC	All	II,III,IV	+0.025	.013	4	view →
ESCA	All	All	−0.191	.007	2	view →
BRCA	All	III,IV	−0.066	.010	2	view →
LUAD	Female	II,III,IV	−0.060	.033	2	view →
THCA	All	All	−0.026	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

OR52H1–LUSC

Open the LUSC breakdown →