OR52H1

Across TCGA patient cohorts, OR52H1 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52H1-associated genes across cancer lineages are Caspase-7-cleavedD198, MEK1, and Annexin-1. Each is linked with OR52H1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52H1-to-partner and partner-to-OR52H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by OR52H1-low versus OR52H1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52H1→partner) and Y-score (partner→OR52H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.904	+3.720	<.001	<.001	3	3
UCEC	MEK1 →	+0.453	+2.321	.002	.006	3	2
UCEC	Annexin-1 →	+0.891	+3.720	<.001	<.001	3	2
UCEC	4E-BP1 →	+0.295	+3.351	.008	.005	3	2
SKCM	PR →	-0.079	-3.305	.039	.009	3	2
UCEC	eIF4E →	+0.198	+2.321	.023	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Caspase-7-cleavedD198 by OR52H1 expression — UCEC

Explore this box plot interactively →