OR52H1

Across TCGA cell cohorts, OR52H1 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR52H1-associated genes across cancer lineages are EPPIN, LUZP4, and IFNA6. Each is linked with OR52H1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52H1-to-partner and partner-to-OR52H1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by OR52H1-low versus OR52H1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52H1→partner) and Y-score (partner→OR52H1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.004	+3.922	.004	.002	3	1
BLOOD_Leukemia	LUZP4 →	+0.322	+3.475	<.001	.006	3	1
BLOOD_Leukemia	IFNA6 →	+0.214	+3.475	<.001	.006	3	1
BLOOD_Leukemia	LRCH2 →	+0.473	+3.807	.001	.007	3	1
BLOOD_Leukemia	TRIM48 →	+0.173	+3.684	<.001	.004	3	1
BLOOD_Leukemia	ENPP6 →	+0.404	+3.667	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

EPPIN by OR52H1 expression — BLOOD_Leukemia

Explore this box plot interactively →