Across TCGA patient cohorts, OR52E6 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52E6-associated genes across cancer lineages are Chk2_pT68, STAT3_pY705, and ASNS. Each is linked with OR52E6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52E6-to-partner and partner-to-OR52E6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E6→partner) and Y-score (partner→OR52E6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Chk2_pT68 →	+0.100	+2.879	.048	.030	3	2
UCEC	STAT3_pY705 →	-0.466	-2.459	<.001	.018	3	2
UCEC	ASNS →	+0.625	+2.321	<.001	.033	3	2
UCEC	Caspase-8 →	-0.219	-3.295	.046	.009	3	2
SKCM	FoxM1 →	+0.164	+1.584	.025	.018	3	2
LUSC	ER-alpha_pS118 →	+0.111	+3.183	.007	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

OR52E6 survival (RNA) · tumor vs normal (RNA) · all OR52E6 data types