Across TCGA cell cohorts, OR52E6 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52E6-associated genes across cancer lineages are IL36A, OR7G3, and FAM25A. Each is linked with OR52E6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52E6-to-partner and partner-to-OR52E6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52E6→partner) and Y-score (partner→OR52E6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	IL36A →	+0.020	+4.643	<.001	.004	3	1
LUNG_SCLC	OR7G3 →	+0.047	+4.643	<.001	.004	3	1
LUNG_SCLC	FAM25A →	+0.140	+4.643	<.001	.004	3	1
LUNG_SCLC	OPN1MW3 →	+0.010	+4.643	<.001	.004	3	1
LARGE_INTESTINE	ASPA →	+0.597	+2.874	<.001	.008	3	1
LARGE_INTESTINE	OR12D3 →	+0.002	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

OR52E6 survival (RNA) · tumor vs normal (RNA) · all OR52E6 data types