OR52D1

Across TCGA patient cohorts, OR52D1 mutation is significantly associated with the RNA expression of many other genes, with 2,339 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52D1-associated genes across cancer lineages are CWC25, CYFIP1, and AATF. Each is linked with OR52D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52D1-to-partner and partner-to-OR52D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CWC25 grouped by OR52D1-low versus OR52D1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52D1→partner) and Y-score (partner→OR52D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CWC25 →	+0.423	+2.119	.002	.003	3	2
UCEC	CYFIP1 →	+0.492	+2.724	.003	.003	3	2
UCEC	AATF →	+0.428	+2.087	.002	.006	3	2
UCEC	PIGW →	+0.755	+2.595	<.001	<.001	3	2
SKCM	LINC01775 →	+0.589	+2.925	<.001	.001	3	2
UCEC	PPIL2 →	+0.449	+2.922	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,339 associations by consensus.

CWC25 by OR52D1 expression — UCEC

Explore this box plot interactively →