OR52D1

Across TCGA cell cohorts, OR52D1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52D1-associated genes across cancer lineages are DEFB134, ARGFX, and C17orf98. Each is linked with OR52D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52D1-to-partner and partner-to-OR52D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB134 grouped by OR52D1-low versus OR52D1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52D1→partner) and Y-score (partner→OR52D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	DEFB134 →	+0.070	+4.371	<.001	.005	3	1
LARGE_INTESTINE	ARGFX →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	C17orf98 →	+0.103	+3.793	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DEFB134 by OR52D1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →