Across TCGA patient cohorts, OR52B6 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52B6-associated genes across cancer lineages are 14-3-3_beta, ACC1, and p90 RSK. Each is linked with OR52B6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52B6-to-partner and partner-to-OR52B6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52B6→partner) and Y-score (partner→OR52B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.125	-3.143	.010	.018	3	1
UCEC	ACC1 →	+0.509	+3.013	.003	.018	3	1
UCEC	p90 RSK →	+0.218	+2.999	.018	.035	3	1
UCEC	PRAS40_pT246 →	+0.187	+2.472	.024	.011	3	1
UCEC	Tuberin_pT1462 →	+0.223	+2.179	.046	.034	3	1
UCEC	ACC_pS79 →	+0.519	+3.009	.001	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

OR52B6 survival (RNA) · tumor vs normal (RNA) · all OR52B6 data types