OR52B6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR52B6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR52B6-associated genes across cancer lineages are PHOX2B, CHRNA2, and TMEM95. Each is linked with OR52B6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR52B6-to-partner and partner-to-OR52B6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52B6→partner) and Y-score (partner→OR52B6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPHOX2B →+0.024+3.658.004.00531
LARGE_INTESTINECHRNA2 →+0.069+3.453<.001.00931
LARGE_INTESTINETMEM95 →+0.016+4.022<.001.00631
BREASTFIGLA →+0.208+4.421.002.00431
SKINUSP17L17 →+0.008+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration