OR51T1

Across TCGA patient cohorts, OR51T1 mutation is significantly associated with the RNA expression of many other genes, with 2,714 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51T1-associated genes across cancer lineages are KIF18A, ZSCAN2, and INCENP. Each is linked with OR51T1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51T1-to-partner and partner-to-OR51T1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIF18A grouped by OR51T1-low versus OR51T1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51T1→partner) and Y-score (partner→OR51T1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF18A →	+0.808	+4.098	<.001	<.001	3	3
UCEC	ZSCAN2 →	+0.452	+3.354	.001	.005	3	3
UCEC	INCENP →	+0.848	+3.708	<.001	<.001	3	3
UCEC	CHEK1 →	+0.736	+3.343	<.001	.005	3	3
UCEC	NUP205 →	+0.752	+3.502	<.001	.002	3	3
UCEC	ZFPL1 →	+0.444	+2.343	.007	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,714 associations by consensus.

KIF18A by OR51T1 expression — UCEC

Explore this box plot interactively →