OR51Q1

Across TCGA patient cohorts, OR51Q1 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51Q1-associated genes across cancer lineages are ASNS, VHL, and Caspase-7-cleavedD198. Each is linked with OR51Q1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51Q1-to-partner and partner-to-OR51Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by OR51Q1-low versus OR51Q1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51Q1→partner) and Y-score (partner→OR51Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASNS →	+0.927	+3.459	<.001	.005	3	3
UCEC	VHL →	-0.687	-3.169	.020	.019	3	2
UCEC	Caspase-7-cleavedD198 →	+0.902	+2.827	<.001	.001	3	2
SKCM	ACC1 →	+0.328	+2.182	.012	.033	3	2
SKCM	TFRC →	+0.569	+4.000	.015	<.001	3	2
SKCM	Cyclin-B1 →	+0.550	+2.472	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

ASNS by OR51Q1 expression — LUAD

Explore this box plot interactively →