OR51Q1

Across TCGA cell cohorts, OR51Q1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible OR51Q1-associated genes across cancer lineages are OR1C1, BOD1L2, and C7orf33. Each is linked with OR51Q1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51Q1-to-partner and partner-to-OR51Q1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1C1 grouped by OR51Q1-low versus OR51Q1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51Q1→partner) and Y-score (partner→OR51Q1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR1C1 →	+0.016	+4.906	<.001	.006	3	1
OESOPHAGUS	BOD1L2 →	+0.006	+4.906	<.001	.006	3	1
UPPER_AERODIGESTIVE_TRACT	C7orf33 →	+0.069	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	APOC4 →	+0.064	+4.736	<.001	.009	3	1
LUNG_NSCLC_LUAD	RESP18 →	+0.033	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	SMIM9 →	+0.024	+4.734	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR1C1 by OR51Q1 expression — OESOPHAGUS

Explore this box plot interactively →