OR51L1

Across TCGA patient cohorts, OR51L1 mutation is significantly associated with the RNA expression of many other genes, with 1,668 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51L1-associated genes across cancer lineages are COPS8P1, MED14P1, and MRPS21P3. Each is linked with OR51L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51L1-to-partner and partner-to-OR51L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPS8P1 grouped by OR51L1-low versus OR51L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51L1→partner) and Y-score (partner→OR51L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COPS8P1 →	+0.144	+2.678	<.001	.003	3	3
READ	MED14P1 →	+0.340	+5.653	<.001	.003	3	2
LIHC	MRPS21P3 →	+0.223	+3.832	<.001	.009	3	2
LIHC	RPSAP35 →	+0.070	+5.317	<.001	.002	3	2
LIHC	RN7SL156P →	+0.092	+4.293	<.001	.009	3	2
LIHC	MIR3660 →	+0.294	+4.423	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,668 associations by consensus.

COPS8P1 by OR51L1 expression — UCEC

Explore this box plot interactively →