OR51L1

Across TCGA cell cohorts, OR51L1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible OR51L1-associated genes across cancer lineages are FAM47C, LYZL2, and CRYGB. Each is linked with OR51L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51L1-to-partner and partner-to-OR51L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47C grouped by OR51L1-low versus OR51L1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51L1→partner) and Y-score (partner→OR51L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	2
LUNG_SCLC	LYZL2 →	+0.020	+4.643	<.001	.004	3	1
LUNG_SCLC	CRYGB →	+0.062	+4.643	<.001	.004	3	1
LUNG_SCLC	C16orf90 →	+0.066	+4.044	<.001	.009	3	1
LUNG_SCLC	TBC1D3H →	+0.325	+4.269	<.001	.005	3	1
LARGE_INTESTINE	OR2T35 →	+0.036	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FAM47C by OR51L1 expression — SKIN

Explore this box plot interactively →