OR51I1

Across TCGA patient cohorts, OR51I1 mutation is significantly associated with the RNA expression of many other genes, with 760 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR51I1-associated genes across cancer lineages are NCAPH2, NDUFAF5, and SH3GL1. Each is linked with OR51I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51I1-to-partner and partner-to-OR51I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCAPH2 grouped by OR51I1-low versus OR51I1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51I1→partner) and Y-score (partner→OR51I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH2 →	+0.519	+3.584	.005	.003	3	2
UCEC	NDUFAF5 →	+0.410	+3.222	.003	.009	3	2
UCEC	SH3GL1 →	+0.471	+3.627	.004	.001	3	2
LUSC	LINC02871 →	+0.341	+3.247	<.001	.008	3	2
SKCM	CRYBB2P1 →	+0.368	+2.298	<.001	<.001	3	2
SKCM	TTLL1 →	+0.380	+1.935	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 760 associations by consensus.

NCAPH2 by OR51I1 expression — UCEC

Explore this box plot interactively →