OR51I1

Across TCGA patient cohorts, OR51I1 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51I1-associated genes across cancer lineages are N-Ras, PAI-1, and CD20. Each is linked with OR51I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51I1-to-partner and partner-to-OR51I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-Ras grouped by OR51I1-low versus OR51I1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51I1→partner) and Y-score (partner→OR51I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	N-Ras →	+0.125	+2.321	.010	.032	3	2
UCEC	PAI-1 →	+0.597	+3.169	<.001	.019	3	1
UCEC	CD20 →	+0.176	+2.827	.010	.035	3	1
SKCM	ACC_pS79 →	+0.242	+3.459	.020	.004	3	1
SKCM	p38-MAPK_pT180_Y182 →	-0.310	-2.568	.013	.009	3	1
SKCM	PREX1 →	-0.270	-1.906	.021	.014	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

N-Ras by OR51I1 expression — SKCM

Explore this box plot interactively →