OR51I1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51I1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR51I1-associated genes across cancer lineages are PRSS54, SLC22A12, and C16orf90. Each is linked with OR51I1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51I1-to-partner and partner-to-OR51I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS54 grouped by OR51I1-low versus OR51I1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51I1→partner) and Y-score (partner→OR51I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaPRSS54 →+0.027+4.539<.001.00732
BLOOD_LeukemiaSLC22A12 →+0.004+4.539<.001.00732
BLOOD_LeukemiaC16orf90 →+0.031+4.152.003.00932
BLOOD_LeukemiaOR1M1 →+0.014+4.969.002.00331
BLOOD_LeukemiaOR9I1 →+0.009+4.539<.001.00731
BLOOD_LeukemiaOR10H5 →+0.054+5.507<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

PRSS54 by OR51I1 expression — BLOOD_Leukemia

Box plot of PRSS54 in OR51I1-low vs OR51I1-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration