OR51G2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR51G2 mutation is significantly associated with the RNA expression of many other genes, with 2,611 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51G2-associated genes across cancer lineages are GKAP1, TTC32, and NEIL3. Each is linked with OR51G2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51G2-to-partner and partner-to-OR51G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GKAP1 grouped by OR51G2-low versus OR51G2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51G2→partner) and Y-score (partner→OR51G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGKAP1 →+0.533+2.010.002.00633
SKCMTTC32 →+0.552+2.087<.001.00533
UCECNEIL3 →+0.623+2.823.001.00133
UCECDDX55 →+0.527+2.502<.001.00233
UCECSUDS3 →+0.479+2.732.001.00333
UCECPPP2R5D →+0.442+2.823.005.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,611 associations by consensus.

GKAP1 by OR51G2 expression — UCEC

Box plot of GKAP1 in OR51G2-low vs OR51G2-high samples in UCEC.

Explore this box plot interactively →

Exploration