OR51G2

Across TCGA patient cohorts, OR51G2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51G2-associated genes across cancer lineages are TSC1, ATM, and VHL. Each is linked with OR51G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51G2-to-partner and partner-to-OR51G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSC1 grouped by OR51G2-low versus OR51G2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51G2→partner) and Y-score (partner→OR51G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSC1 →	-0.184	-2.960	.017	.035	3	2
UCEC	ATM →	-0.609	-3.156	.002	.018	3	2
SKCM	VHL →	-0.657	-3.584	.010	.002	3	2
SKCM	Caveolin-1 →	-0.550	-1.765	.017	.013	3	2
UCEC	eIF4G →	+0.302	+3.169	.030	.018	3	1
UCEC	MEK1 →	+0.485	+2.700	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

TSC1 by OR51G2 expression — UCEC

Explore this box plot interactively →