OR51G2

Across TCGA cell cohorts, OR51G2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OR51G2-associated genes across cancer lineages are NKX2-6, PIWIL3, and TBC1D3G. Each is linked with OR51G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51G2-to-partner and partner-to-OR51G2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NKX2-6 grouped by OR51G2-low versus OR51G2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51G2→partner) and Y-score (partner→OR51G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NKX2-6 →	+0.591	+5.201	<.001	.006	3	2
SKIN	PIWIL3 →	+0.022	+2.933	<.001	.003	3	1
SKIN	TBC1D3G →	+0.760	+2.841	<.001	.009	3	1
LARGE_INTESTINE	SCYGR1 →	+0.133	+4.437	<.001	.004	3	1
LUNG_SCLC	DEFB132 →	+0.019	+5.029	<.001	.006	3	1
BLOOD_Leukemia	MYF5 →	+0.013	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

NKX2-6 by OR51G2 expression — BLOOD_Leukemia

Explore this box plot interactively →