OR51F2

Across TCGA cell cohorts, OR51F2 mutation is significantly associated with the mutation status of many other genes, with 2,188 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51F2-associated genes across cancer lineages are NR1H4, DOCK10, and ADCY8. Each is linked with OR51F2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR51F2-to-partner and partner-to-OR51F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NR1H4 grouped by OR51F2-low versus OR51F2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51F2→partner) and Y-score (partner→OR51F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	NR1H4 →	+5.894	+5.321	.002	.002	1	4
LARGE_INTESTINE	DOCK10 →	+1.584	+2.769	.008	.008	1	4
LARGE_INTESTINE	ADCY8 →	+2.125	+3.278	.001	.001	1	4
LARGE_INTESTINE	ERCC6 →	+2.000	+2.662	.008	.008	1	4
BLOOD_Leukemia	EPHA7 →	+3.479	+4.932	.002	.002	1	3
STOMACH	CDH11 →	+4.807	+4.807	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,188 associations by consensus.

NR1H4 by OR51F2 expression — BLOOD_Leukemia

Explore this box plot interactively →