OR51F1

Across TCGA patient cohorts, OR51F1 mutation is significantly associated with the RNA expression of many other genes, with 517 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51F1-associated genes across cancer lineages are ARPC5L, TUBGCP4, and ANAPC15. Each is linked with OR51F1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR51F1-to-partner and partner-to-OR51F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARPC5L grouped by OR51F1-low versus OR51F1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51F1→partner) and Y-score (partner→OR51F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARPC5L →	+0.605	+3.191	<.001	.009	3	2
UCEC	TUBGCP4 →	+0.675	+3.459	<.001	.005	3	2
SKCM	ANAPC15 →	+0.349	+3.182	.006	.009	3	2
SKCM	ITGB1BP1 →	+0.435	+2.279	.001	.001	3	2
SKCM	PARP2 →	+0.423	+1.867	.002	.005	3	2
SKCM	WDR74 →	+0.382	+2.743	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

ARPC5L by OR51F1 expression — UCEC

Explore this box plot interactively →