OR51B2

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, OR51B2 mutation is significantly associated with the mutation status of many other genes, with 844 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR51B2-associated genes across cancer lineages are DOCK4, CATSPERE, and MTO1. Each is linked with OR51B2 in more than 3 cancer types. Because this analysis shows association rather than direction, both OR51B2-to-partner and partner-to-OR51B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DOCK4 grouped by OR51B2-low versus OR51B2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51B2→partner) and Y-score (partner→OR51B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYDOCK4 →+4.415+4.977.007.00714
LUNG_NSCLC_LUADCATSPERE →+4.339+4.339.009.00914
OVARYMTO1 →+5.415+5.415.004.00413
LARGE_INTESTINEAGMO →+4.584+3.350.003.00313
LARGE_INTESTINEKIF21A →+3.000+3.906<.001<.00113
LARGE_INTESTINEKCNH7 →+3.000+3.906<.001<.00113
Each partner links to its Q-omics profile. Showing the 6 strongest of 844 associations by consensus.

DOCK4 by OR51B2 expression — OVARY

Box plot of DOCK4 in OR51B2-low vs OR51B2-high samples in OVARY.

Explore this box plot interactively →

Exploration