OR51A7

Across TCGA patient cohorts, OR51A7 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR51A7-associated genes across cancer lineages are MEK1, ASNS, and C-Raf. Each is linked with OR51A7 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR51A7-to-partner and partner-to-OR51A7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by OR51A7-low versus OR51A7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR51A7→partner) and Y-score (partner→OR51A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.366	+2.115	.015	.017	3	2
UCEC	ASNS →	+0.414	+2.321	.005	.033	3	2
UCEC	C-Raf →	+0.189	+2.584	.001	.010	3	2
UCEC	A-Raf_pS299 →	-0.145	-2.321	.003	.006	3	1
UCEC	FoxM1 →	+0.229	+2.321	.031	.006	3	1
UCEC	Ku80 →	+0.234	+2.335	.016	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MEK1 by OR51A7 expression — UCEC

Explore this box plot interactively →